A22439
Size
  • 50ul
  • 100ul
Price
  • $129
  • $229
Qty
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Product description

function:May play a role in actin remodeling. Involved in the dissociation of the integrin-tensin-actin complex. EGF activates TNS4 and down-regulates TNS3 which results in capping the tail of ITGB1. Seems to be involved in mammary cell migration. May be

Source
Rabbit
Applications
IHC,IF,ELISA
Reactivity
Human
Dilution
IHC: 1/100 - 1/300. IF: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Storage
-20°C/1 year
Specificity
Tensin3 Polyclonal Antibody detects endogenous levels of Tensin3 protein.
Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
The antiserum was produced against synthesized peptide derived from human TENS3. AA range:541-590
Uniprot No
Q68CZ2
Alternative names
TNS3; TEM6; TENS1; TPP; Tensin-3; Tensin-like SH2 domain-containing protein 1; Tumor endothelial marker 6
Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Background
function:May play a role in actin remodeling. Involved in the dissociation of the integrin-tensin-actin complex. EGF activates TNS4 and down-regulates TNS3 which results in capping the tail of ITGB1. Seems to be involved in mammary cell migration. May be
Other
Gene_name: TNS3 ; Protein_name: Tensin-3; Expression: Amygdala,Brain,Epithelium,Kidney,Placenta,Spleen,Testis,
Mol.Wt (Da)
30 kD
Concentration
1 mg/ml

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