A21549
Size
  • 50ul
  • 100ul
Price
  • $129
  • $229
Qty
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Product description

function:Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN

Source
Rabbit
Applications
WB,IF,ELISA
Reactivity
Human
Dilution
WB: 1/500 - 1/2000. IF: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Storage
-20°C/1 year
Specificity
Sin3B Polyclonal Antibody detects endogenous levels of Sin3B protein.
Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
The antiserum was produced against synthesized peptide derived from human SIN3B. AA range:221-270
Uniprot No
O75182
Alternative names
SIN3B; KIAA0700; Paired amphipathic helix protein Sin3b; Histone deacetylase complex subunit Sin3b; Transcriptional corepressor Sin3b
Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Background
function:Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN
Other
Gene_name: SIN3B ; Protein_name: Paired amphipathic helix protein Sin3b; Expression: Brain,Duodenum,Lung,Skin,
Mol.Wt (Da)
157 kD
Concentration
1 mg/ml

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