

Product description
function:Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its
Source
Rabbit
Applications
WB,ELISA
Reactivity
Human,Rat,Mouse
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Storage
-20°C/1 year
Specificity
SIGIR Polyclonal Antibody detects endogenous levels of protein.
Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
Synthesized peptide derived from part region of human protein
Uniprot No
Q6IA17
Form
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Clonality
Polyclonal
Background
function:Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its
Other
Gene_name: SIGIRR UNQ301/PRO342 ; Protein_name: Single Ig IL-1-related receptor (Single Ig IL-1R-related molecule) (Single immunoglobulin domain-containing IL1R-related protein) (Toll/interleukin-1 receptor 8) (TIR8); Expression: Colon,Lung,Pancreas,
Mol.Wt (Da)
22 kD
Concentration
1 mg/ml
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