A21487
Size
  • 50ul
  • 100ul
Price
  • $129
  • $229
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Product description

domain:The SH2 domain preferentially binds phosphopeptides with the consensus sequence Y-[TVI]-X-L and mediates interaction with PDGFRA, PDGFRB, FGRFR1, IL2RB, IL2RG, CD3Z and CRK/CrKII.,function:Adapter protein which regulates several signal transduction

Source
Rabbit
Applications
WB,ELISA
Reactivity
Human,Mouse
Dilution
WB: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Storage
-20°C/1 year
Specificity
Phospho-Shb (Y246) Polyclonal Antibody detects endogenous levels of Shb protein only when phosphorylated at Y246.
Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
Synthesized phospho-peptide around the phosphorylation site of human Shb (phospho Tyr246)
Uniprot No
Q15464
Alternative names
SHB; SH2 domain-containing adapter protein B
Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Background
domain:The SH2 domain preferentially binds phosphopeptides with the consensus sequence Y-[TVI]-X-L and mediates interaction with PDGFRA, PDGFRB, FGRFR1, IL2RB, IL2RG, CD3Z and CRK/CrKII.,function:Adapter protein which regulates several signal transduction
Other
Gene_name: SHB ; Protein_name: SH2 domain-containing adapter protein B; Expression: Epithelium,Fetal brain,Placenta,
Mol.Wt (Da)
55 kD
Concentration
1 mg/ml

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