

Product description
function:Guanine nucleotide exchange factor (GEF) for Rap1A, Rap2A and M-Ras GTPases. Does not interact with cAMP.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 cyclic nucleotide-binding domain.,similarity:Contains 1 N-
Source
Rabbit
Applications
WB,ELISA
Reactivity
Human
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Storage
-20°C/1 year
Specificity
RPGF6 Polyclonal Antibody detects endogenous levels of protein.
Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
Synthesized peptide derived from human protein . at AA range: 460-540
Uniprot No
Q8TEU7
Form
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Clonality
Polyclonal
Background
function:Guanine nucleotide exchange factor (GEF) for Rap1A, Rap2A and M-Ras GTPases. Does not interact with cAMP.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 cyclic nucleotide-binding domain.,similarity:Contains 1 N-
Other
Gene_name: RAPGEF6 PDZGEF2 ; Protein_name: Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2); Expression: Brain,Clones donated by RIKEN,Epithelium,Fetal brain,PCR re
Mol.Wt (Da)
141 kD
Concentration
1 mg/ml
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