

Product description
domain:The RING finger domain, in addition to its role in ubiquitination, functions as a structural scaffold to bring two clusters of positive-charged residues within spatial proximity to mimic a bipartite nuclear localization signal (NLS).,function:E3 ub
Source
Rabbit
Applications
WB,ELISA
Reactivity
Human,Mouse
Dilution
WB: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Storage
-20°C/1 year
Specificity
COP1 Polyclonal Antibody detects endogenous levels of COP1 protein.
Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
The antiserum was produced against synthesized peptide derived from human RFWD2. AA range:353-402
Uniprot No
Q8NHY2
Alternative names
RFWD2; COP1; RNF200; E3 ubiquitin-protein ligase RFWD2; Constitutive photomorphogenesis protein 1 homolog; hCOP1; RING finger and WD repeat domain protein 2; RING finger protein 200
Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Background
domain:The RING finger domain, in addition to its role in ubiquitination, functions as a structural scaffold to bring two clusters of positive-charged residues within spatial proximity to mimic a bipartite nuclear localization signal (NLS).,function:E3 ub
Other
Gene_name: RFWD2 ; Protein_name: E3 ubiquitin-protein ligase RFWD2; Expression: Hepatoma,Spleen,Testis,
Mol.Wt (Da)
110 kD
Concentration
1 mg/ml
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