

Product description
caspase 8(CASP8) Homo sapiens This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzy
Source
Rabbit
Applications
WB,IHC,IF,ELISA
Reactivity
Human
Dilution
WB 1:500-2000, IF 1:50-300, IHC 1:50-300
Storage
-20°C/1 year
Specificity
Cleaved-Caspase-8 (D384) Polyclonal Antibody detects endogenous levels of fragment of activated Caspase-8 protein resulting from cleavage adjacent to D384.
Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
The antiserum was produced against synthesized peptide derived from human Caspase 8. AA range:335-384
Uniprot No
Q14790
Alternative names
CASP8; MCH5; Caspase-8; CASP-8; Apoptotic cysteine protease; Apoptotic protease Mch-5; CAP4; FADD-homologous ICE/ced-3-like protease; FADD-like ICE; FLICE; ICE-like apoptotic protease 5; MORT1-associated ced-3 homolog; MACH
Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Background
caspase 8(CASP8) Homo sapiens This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzy
Other
Gene_name: CASP8 ; Protein_name: Caspase-8; Expression: B-cell,Leukocyte,Lung,T-cell,Thymus,
Mol.Wt (Da)
47+55 kD
Concentration
1 mg/ml
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