

Product description
checkpoint kinase 2(CHEK2) Homo sapiens In response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators. The protein encoded by this gene is a cell cycle checkpoint regulator
Source
Rabbit
Applications
IF,WB,IHC,ELISA
Reactivity
Human,Mouse,Rat
Dilution
IF: 1:50-200 WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Storage
-20°C/1 year
Specificity
Phospho-Chk2 (T68) Polyclonal Antibody detects endogenous levels of Chk2 protein only when phosphorylated at T68.
Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
The antiserum was produced against synthesized peptide derived from human Chk2 around the phosphorylation site of Thr68. AA range:35-84
Uniprot No
O96017
Alternative names
CHEK2; CDS1; CHK2; RAD53; Serine/threonine-protein kinase Chk2; CHK2 checkpoint homolog; Cds1 homolog; Hucds1; hCds1; Checkpoint kinase 2
Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Background
checkpoint kinase 2(CHEK2) Homo sapiens In response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators. The protein encoded by this gene is a cell cycle checkpoint regulator
Other
Gene_name: CHEK2 ; Protein_name: Serine/threonine-protein kinase Chk2; Expression: Colon carcinoma,Mammary gland,Muscle,T-cell,
Mol.Wt (Da)
61 kD
Concentration
1 mg/ml
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