A11639
Size
  • 50ul
  • 100ul
Price
  • $129
  • $229
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Product description

caspase 8(CASP8) Homo sapiens This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzy

Source
Rabbit
Applications
WB,IHC,ELISA
Reactivity
Human,Rat
Dilution
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Storage
-20°C/1 year
Specificity
Phospho-Caspase-8 (S347) Polyclonal Antibody detects endogenous levels of Caspase-8 protein only when phosphorylated at S347.
Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
The antiserum was produced against synthesized peptide derived from human Caspase 8 around the phosphorylation site of Ser347. AA range:313-362
Uniprot No
Q14790
Alternative names
CASP8; MCH5; Caspase-8; CASP-8; Apoptotic cysteine protease; Apoptotic protease Mch-5; CAP4; FADD-homologous ICE/ced-3-like protease; FADD-like ICE; FLICE; ICE-like apoptotic protease 5; MORT1-associated ced-3 homolog; MACH
Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Background
caspase 8(CASP8) Homo sapiens This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzy
Other
Gene_name: CASP8 ; Protein_name: Caspase-8; Expression: B-cell,Leukocyte,Lung,T-cell,Thymus,
Mol.Wt (Da)
55 kD
Concentration
1 mg/ml

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