A11359
Size
  • 50ul
  • 100ul
Price
  • $129
  • $229
Qty
Product description

Bruton tyrosine kinase(BTK) Homo sapiens The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to prod

Source
Rabbit
Applications
WB,ELISA
Reactivity
Human,Mouse,Rat
Dilution
WB: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Storage
-20°C/1 year
Specificity
Phospho-Btk (Y223) Polyclonal Antibody detects endogenous levels of Btk protein only when phosphorylated at Y223.
Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
The antiserum was produced against synthesized peptide derived from human BTK around the phosphorylation site of Tyr223. AA range:188-237
Uniprot No
Q06187
Alternative names
BTK; AGMX1; ATK; BPK; Tyrosine-protein kinase BTK; Agammaglobulinaemia tyrosine kinase; ATK; B-cell progenitor kinase; BPK; Bruton tyrosine kinase
Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Background
Bruton tyrosine kinase(BTK) Homo sapiens The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to prod
Other
Gene_name: BTK ; Protein_name: Tyrosine-protein kinase BTK; Expression: BCR-ABL1+ pre-B lymphoblastic leukemia,Blood,Platelet,Small intestine,
Mol.Wt (Da)
80 kD
Concentration
1 mg/ml