

Product description
BRCA1, DNA repair associated(BRCA1) Homo sapiens This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA d
Source
Rabbit
Applications
WB,ELISA
Reactivity
Human
Dilution
WB: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Storage
-20°C/1 year
Specificity
Phospho-BRCA1 (S1457) Polyclonal Antibody detects endogenous levels of BRCA1 protein only when phosphorylated at S1457.
Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
The antiserum was produced against synthesized peptide derived from human BRCA1 around the phosphorylation site of Ser1457. AA range:1423-1472
Uniprot No
P38398
Alternative names
BRCA1; RNF53; Breast cancer type 1 susceptibility protein; RING finger protein 53
Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Background
BRCA1, DNA repair associated(BRCA1) Homo sapiens This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA d
Other
Gene_name: BRCA1 ; Protein_name: Breast cancer type 1 susceptibility protein; Expression: Bladder,Blood,Epithelium,Mammary gland,PCR rescued clones,Peripheral Nervou
Mol.Wt (Da)
208 kD
Concentration
1 mg/ml
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