

Product description
function:Plays a role in inhibiting the effects of BCL10-induced activation of NF-kappa-B. May inhibit the phosphorylation of BCL10 in a CARD-dependent manner.,PTM:Isoform 2 is phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1
Source
Rabbit
Applications
IHC,ELISA
Reactivity
Human,Mouse
Dilution
IHC: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Storage
-20°C/1 year
Specificity
BinCARD Polyclonal Antibody detects endogenous levels of BinCARD protein.
Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
The antiserum was produced against synthesized peptide derived from human C9orf89. AA range:21-70
Uniprot No
Q96LW7
Alternative names
C9orf89; Bcl10-interacting CARD protein; BinCARD
Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Background
function:Plays a role in inhibiting the effects of BCL10-induced activation of NF-kappa-B. May inhibit the phosphorylation of BCL10 in a CARD-dependent manner.,PTM:Isoform 2 is phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1
Other
Gene_name: C9orf89 ; Protein_name: Bcl10-interacting CARD protein; Expression: Blood,Placenta,Skin,Uterus,
Mol.Wt (Da)
26 kD
Concentration
1 mg/ml
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